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Jess Moerland

Jess Moerland

Doctoral Candidate
Year Start: 2019
Degree: PhD
External Mentor: Karen Liby

Employment

Postdoctoral fellow, Indiana University Indianapolis, Indianapolis, 2025 - Present

Publications

Synthetic Oleanane Triterpenoids Reduce Tumor Growth and Promote an Anti-Tumor Immune Response Independent of Cancer KEAP1 Mutational Status Antioxidants (2025)

Synthetic Oleanane Triterpenoids Reduce Tumor Growth and Promote an Anti-Tumor Immune Response Independent of Cancer KEAP1 Mutational Status Antioxidants (2025)

The RXR Agonist MSU-42011 Reduces Tumor Burden in a Murine Preclinical NF1-Deficient Model Cancers (2025)

The Triterpenoid CDDO-Methyl Ester Reduces Tumor Burden, Reprograms the Immune Microenvironment, and Protects from Chemotherapy-Induced Toxicity in a Preclinical Mouse Model of Established Lung Cancer Antioxidants (2024)

The Multi-Faceted Consequences of NRF2 Activation throughout Carcinogenesis Molecules and Cells (2023)

The Triterpenoid CDDO-Methyl Ester Redirects Macrophage Polarization and Reduces Lung Tumor Burden in a Nrf2-Dependent Manner Antioxidants (2023)

The rexinoid V-125 reduces tumor growth in preclinical models of breast and lung cancer Scientific Reports (2022)

The RXR Agonist MSU42011 Is Effective for the Treatment of Preclinical HER2+ Breast Cancer and Kras-Driven Lung Cancer Cancers (2021)

Sustained, local delivery of the PARP inhibitor talazoparib prevents the development of mammary gland hyperplasia in Brca1-deficient mice Scientific Reports (2021)

Potential therapeutic uses of rexinoids Advances in Immunopharmacology (2021)

The novel rexinoid MSU-42011 is effective for the treatment of preclinical Kras-driven lung cancer Scientific Reports (2020)

Retinoid X receptor agonist LG100268 modulates the immune microenvironment in preclinical breast cancer models npj Breast Cancer (2019)

In the News

Jess Moerland Successfully Defends Her Dissertation

Jess Moerland successfully defended her dissertation Jan. 30. Her topic was “Pharmacological Nrf2 Activation Reprograms the Immune Microenvironment and Decreases Tumor Burden in KRAS-Driven Lung Cancer." Congratulations Dr. Moerland on a job well done.