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Stephanie Watts

Stephanie Watts , PhD FAHA

she/her/hers
Professor
Pharmacology & Toxicology
B445 Life Sciences

Education

PhD, Pharmacology and Toxicology, Indiana University Indianapolis,
BS, Chemistry, The University of Illinois,
Postdoctoral Fellow, Physiology, The University of Michigan,

Employment

Professor, Michigan State University, East Lansing, 1995 - Present

Publications

Presence and Variability of the Microbiome in Perivascular Adipose Tissue: A Whole-Genome Sequencing Study in Dahl SS Rats (2026)

5-Hydroxytryptamine may be a viable treatment option for hypertension resistant to diuretic treatment American Journal of Physiology-Heart and Circulatory Physiology (2025)

PVAT adipocyte: energizing, modulating, and structuring vascular function during normotensive and hypertensive states American Journal of Physiology-Heart and Circulatory Physiology (2025)

Perivascular Adipocytes’ Adipogenesis Is Defined by Their Anatomical Location in the Descending Thoracic Aorta Cells (2025)

Mechanotransduction in the Perivascular Adipose Tissue Arteriosclerosis, Thrombosis, and Vascular Biology (2025)

Vascular chemerin from PVAT contributes to norepinephrine and serotonin-induced vasoconstriction and vascular stiffness in a sex-dependent manner American Journal of Physiology-Heart and Circulatory Physiology (2024)

Innervation of adipocytes is limited in mouse perivascular adipose tissue American Journal of Physiology-Heart and Circulatory Physiology (2024)

A cell atlas of thoracic aortic perivascular adipose tissue: a focus on mechanotransducers American Journal of Physiology-Heart and Circulatory Physiology (2024)

How New Developments in Pharmacology Receptor Theory Are Changing (Our Understanding of) Hypertension Therapy American Journal of Hypertension (2024)

Development of a 5-HT7 receptor antibody for the rat: the good, the bad, and the ugly Naunyn-Schmiedeberg's Archives of Pharmacology (2023)

Skin Vascular Resistance Decreases during 5-HT-Induced Hypotension in the Rat Biomedicines (2023)

A high fat diet does not stimulate blood pressure dependence on chemerin in the Sprague-Dawley rat American Heart Journal Plus: Cardiology Research and Practice (2022)

Is the 5-hydroxytryptamine 7 Receptor Constitutively Active in the Vasculature? A Study in Veins/Vein Journal of Cardiovascular Pharmacology (2022)

Divergence of Chemerin Reduction by an ATS9R Nanoparticle Targeting Adipose Tissue In Vitro vs. In Vivo in the Rat Biomedicines (2022)

Aortic stiffness is lower when PVAT is included: a novel ex vivo mechanics study American Journal of Physiology-Heart and Circulatory Physiology (2022)

Male and female high-fat diet-fed Dahl SS rats are largely protected from vascular dysfunctions: PVAT contributions reveal sex differences American Journal of Physiology-Heart and Circulatory Physiology (2021)

Using data to make the case for program resources and sustainability: the BEST action inventory case study SN Social Sciences (2021)

Transglutaminases Are Active in Perivascular Adipose Tissue International Journal of Molecular Sciences (2021)

Blood pressure changes PVAT function and transcriptome: use of the mid-thoracic aorta coarcted rat American Journal of Physiology-Heart and Circulatory Physiology (2020)

Activation of the 5‐HT7 receptor but not nitric oxide synthase is necessary for chronic 5‐hydroxytryptamine‐induced hypotension Experimental Physiology (2020)

Chemerin as a Driver of Hypertension: A Consideration American Journal of Hypertension (2020)

A New Function for Perivascular Adipose Tissue (PVAT): Assistance of Arterial Stress Relaxation Scientific Reports (2020)

Different blood pressure responses in hypertensive rats following chemerin mRNA inhibition in dietary high fat compared to dietary high-salt conditions Physiological Genomics (2019)

5-HT does not lower blood pressure in the 5-HT7 knockout rat Physiological Genomics (2019)

Creation of the 5-hydroxytryptamine receptor 7 knockout rat as a tool for cardiovascular research Physiological Genomics (2019)

Fenfluramine-induced PVAT-dependent contraction depends on norepinephrine and not serotonin Pharmacological Research (2019)

Faculty perceptions and knowledge of career development of trainees in biomedical science: What do we (think we) know? PLOS ONE (2019)

Renal perivascular adipose tissue: Form and function Vascular Pharmacology (2018)

5-HT causes splanchnic venodilation American Journal of Physiology-Heart and Circulatory Physiology (2017)

3T3‐L1 cells and perivascular adipocytes are not equivalent in amine transporter expression FEBS Letters (2017)

Oh, the places you'll go! My many colored serotonin (apologies to Dr. Seuss) American Journal of Physiology-Heart and Circulatory Physiology (2016)

The adipokine chemerin amplifies electrical field-stimulated contraction in the isolated rat superior mesenteric artery American Journal of Physiology-Heart and Circulatory Physiology (2016)

The persistence of active smooth muscle in the female rat cervix through pregnancy American Journal of Obstetrics and Gynecology (2015)

Serotonin and sensory nerves: Meeting in the cardiovascular system Vascular Pharmacology (2014)