Erika Lisabeth , PhD
Education
BS, Chemistry, Michigan State University, 1999
Post-doctoral Training, Cancer Biology, Sanford Burnham Prebys Medical Discovery Institute, 2009
PhD, Chemistry and Biochemistry , University of California, San Diego, 2003
Employment
Assistant Professor, Michigan State University, East Lansing, 2014 - Present
Publications
Pirin does not bind to p65 or regulate NFκB-dependent gene expression but does modulate cellular quercetin levels. Molecular pharmacology (2025)
Reversion of a RND transporter pseudogene uncovers latent stress resistance in Brucella ovis (2025)
AI is a viable alternative to high throughput screening: a 318-target study. Scientific reports (2024)
Development of a Cell-Based AlphaLISA Assay for High-Throughput Screening for Small Molecule Proteasome Modulators. ACS omega (2023)
Development of a 5-HT7 receptor antibody for the rat: the good, the bad, and the ugly. Naunyn-Schmiedeberg's archives of pharmacology (2023)
Mass Spectrometry, Structural Analysis, and Anti-Inflammatory Properties of Photo-Cross-Linked Human Albumin Hydrogels ACS Applied Bio Materials (2022)
Transforming growth factor β1 increases expression of contractile genes in human pulmonary arterial smooth muscle cells by potentiating sphingosine-1-phosphate signaling Molecular Pharmacology (2021)
Rho-mediated signaling promotes BRAF inhibitor resistance in de-differentiated melanoma cells Oncogene (2020)
5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma Journal of Medicinal Chemistry (2019)
Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds ACS Pharmacology and Translational Science (2019)
The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in Kras G12D ; Pdx1-Cre (KC) mice Scientific Reports (2019)
Identification of Pirin as a Molecular Target of the CCG-1423/CCG- 203971 Series of Anti-Fibrotic and Anti-Metastatic Compounds bioRxiv (2018)
Rho-mediated gene transcription promotes BRAF inhibitor resistance in de-differentiated melanoma cells bioRxiv (2018)
Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis Scientific Reports (2017)
Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma Bioorganic and Medicinal Chemistry Letters (2017)
Pharmacological inhibition of myocardin-related transcription factor pathway blocks lung metastases of RhoC-Overexpressing melanoma Molecular Cancer Therapeutics (2017)
Attenuation of Eph receptor kinase activation in cancer cells by coexpressed ephrin ligands PLoS ONE (2013)
Eph receptor signaling and ephrins Cold Spring Harbor Perspectives in Biology (2013)
Cancer somatic mutations disrupt functions of the EphA3 receptor tyrosine kinase through multiple mechanisms Biochemistry (2012)
Flexible regions within IκBα create the ubiquitin-independent degradation signal Journal of Biological Chemistry (2010)
NF-κB dictates the degradation pathway of IκBα EMBO Journal (2008)
NF-κB dictates the degradation pathway of IκBα (EMBO Journal (2008) DOI: 10.1038/emboj.2008.73) EMBO Journal (2008)
Pre-folding IκBα Alters Control of NF-κB Signaling Journal of Molecular Biology (2008)
The Structure of Apo-wild-type Cellular Retinoic Acid Binding Protein II at 1.4 Å and its Relationship to Ligand Binding and Nuclear Translocation Journal of Molecular Biology (2006)
