Sachi Horibata , PhD
Education
PhD, Biological and Biomedical Sciences, Cornell University, 2010
Publications
The Evolving AML Genomic Landscape: Therapeutic Implications. Current cancer drug targets (2020)
Mycoplasma Infection Mediates Sensitivity of Multidrug-Resistant Cell Lines to Tiopronin: A Cautionary Tale. Journal of medicinal chemistry (2020)
Transcriptomic profile of intrinsically chemoresistant acute myeloid leukemia patients. Molecular & cellular oncology (2019)
Heterogeneity in refractory acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America (2019)
A bi-stable feedback loop between GDNF, EGR1, and ERα contribute to endocrine resistant breast cancer. PloS one (2018)
ER-positive breast cancer cells are poised for RET-mediated endocrine resistance. PloS one (2018)
PAD2 overexpression in transgenic mice augments malignancy and tumor-associated inflammation in chemically initiated skin tumors. Cell and tissue research (2017)
Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration. BMC cancer (2017)
A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Cell (2016)
Utilization of the Soft Agar Colony Formation Assay to Identify Inhibitors of Tumorigenicity in Breast Cancer Cells. Journal of visualized experiments : JoVE (2015)
PAD2 overexpression in transgenic mice promotes spontaneous skin neoplasia. Cancer research (2014)
A novel role for protein arginine deiminase 4 in pluripotency: the emerging role of citrullinated histone H1 in cellular programming. BioEssays : news and reviews in molecular, cellular and developmental biology (2014)
MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress. Molecular cancer (2014)
Identification of macrophage extracellular trap-like structures in mammary gland adipose tissue: a preliminary study. Frontiers in immunology (2013)
Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis. Biochemistry research international (2012)
Role for peptidylarginine deiminase enzymes in disease and female reproduction. The Journal of reproduction and development (2012)
Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface. Cancer immunology, immunotherapy : CII (2011)
Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes. Molecular cancer (2010)
MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells. Molecular cancer (2010)
