Carolina de Aguiar Ferreira , PhD

Publications

Preclinical Evaluation of Radium-223 and Immune Checkpoint Inhibitors Using an Immune-Competent Model of Prostate Cancer Bone Metastases Precision Oncology (2026)

Preclinical Evaluation of [ ¹⁷⁷ Lu]Lu-ART-101 for Radiopharmaceutical Therapy of Advanced Prostate Cancer Journal of Nuclear Medicine (2026)

Priming versus propagating: distinct immune effects of alpha- versus beta-particle emitting radiopharmaceuticals when combined with immune checkpoint inhibition in mice Nature Communications (2026)

Radionuclide-Dependent Stimulation of Antitumor Immunity in GD2-Targeted Radiopharmaceutical Therapy Combined with Immune Checkpoint Inhibitors Radiation (2025)

Enhanced Antitumor Efficacy of 225Ac-NM600 Compared to 177Lu-NM600 in Prostate Cancer Models International Journal of Radiation Oncology*Biology*Physics (2025)

Data from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Figure S1 from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Figure S2 from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Figure S3 from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Figure S4 from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Figure S5 from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Figure S6 from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Figure S7 from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Figure S8 from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Figure S9 from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

Supplementary Tables from The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy (2025)

The Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy Cancer Immunology Research (2025)

Immunomodulatory effects of alpha vs beta radiopharmaceutical therapy in murine prostate cancer Frontiers in Immunology (2025)

Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types Scientific Reports (2025)

Tumor Immunity Following Radiopharmaceutical + Checkpoint Blockade Varies with Treatment Sequence, Radioisotope and Tumor Immunogenicity International Journal of Radiation Oncology*Biology*Physics (2024)

EGFR- and Integrin αVβ3-Targeting Peptides as Potential Radiometal-Labeled Radiopharmaceuticals for Cancer Theranostics International Journal of Molecular Sciences (2024)

EGFR- and Integrin α_Vβ₃-Targeting Peptides as Potential Radiometal-Labeled Radiopharmaceuticals for Cancer Theranostics International Journal of Molecular Sciences (2024)

SYNTHESIS, CHARACTERIZATION, AND RADIOLABELING OF MODIFIED PEPTIDE FRAGMENTS TARGETING ΑVΒ3 INTEGRIN ADHESION MOLECULE OVEREXPRESSED IN TUMORS Hematology, Transfusion and Cell Therapy (2024)

Preclinical evaluation of L-fucoside from lapachol-loaded nanoemulsion as a strategy to breast cancer treatment Biomedicine & Pharmacotherapy (2024)

Addition of Peptide Receptor Radiotherapy to Immune Checkpoint Inhibition Therapy Improves Outcomes in Neuroendocrine Tumors Journal of Nuclear Medicine (2023)

HER3 PET Imaging Predicts Response to Pan Receptor Tyrosine Kinase Inhibition Therapy in Gastric Cancer Molecular Imaging and Biology (2023)

Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models Journal of Controlled Release (2023)

Profound immunomodulatory effects of ²²⁵ Ac-NM600 drive enhanced anti-tumor response in prostate cancer (2022)

[68 Ga]Ga-FAPI-46 PET for non-invasive detection of pulmonary fibrosis disease activity European Journal of Nuclear Medicine and Molecular Imaging (2022)

Antitumor efficacy of ⁹⁰Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regulatory T cells in murine prostate tumors Journal for ImmunoTherapy of Cancer (2022)

Immune Checkpoint Inhibitor-Mediated Cancer Theranostics with Radiolabeled Anti-Granzyme B Peptide Pharmaceutics (2022)

ImmunoPET of the differential expression of CD146 in breast cancer. American journal of cancer research (2021)

CD38-Targeted Theranostics of Lymphoma with ⁸⁹Zr/¹⁷⁷Lu-Labeled Daratumumab Advanced Science (2021)

CD38‐Targeted Theranostics of Lymphoma with ⁸⁹Zr/¹⁷⁷Lu‐Labeled Daratumumab Advanced Science (2021)

ImmunoPET of CD146 in Orthotopic and Metastatic Breast Cancer Models Bioconjugate Chemistry (2021)

Non-invasive detection of immunotherapy-induced adverse events Clinical Cancer Research (2021)

Ultrasmall Porous Silica Nanoparticles with Enhanced Pharmacokinetics for Cancer Theranostics Nano Letters (2021)

Voices in Molecular Pharmaceutics: Meet Dr. Carolina Ferreira, Who Is Developing the Next Generation of Radioactive Theranostics Molecular Pharmaceutics (2021)

pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment Biomedicine and Pharmacotherapy (2021)

^86/90Y-Labeled Monoclonal Antibody Targeting Tissue Factor for Pancreatic Cancer Theranostics Molecular Pharmaceutics (2020)

Ag₂WO₄ nanoparticles radiolabeled with technetium-99m: a potential new tool for tumor identification and uptake Journal of Radioanalytical and Nuclear Chemistry (2020)

Ag2WO4 nanoparticles radiolabeled with technetium-99m: a potential new tool for tumor identification and uptake Journal of Radioanalytical and Nuclear Chemistry (2020)

Granzyme B PET imaging for assessment of disease activity in inflammatory bowel disease Journal of Nuclear Medicine (2020)

HER3 PET Imaging Predicts Response to Pan-Receptor Tyrosine Kinase Inhibtion Therapy in Gastric Cancer Journal of Nuclear Medicine (2020)

HPMA-based star polymer biomaterials with tuneable structure and biodegradability tailored for advanced drug delivery to solid tumours Biomaterials (2020)

Internally Responsive Nanomaterials for Activatable Multimodal Imaging of Cancer Advanced Healthcare Materials (2020)

Selenium-Doped Carbon Quantum Dots Act as Broad-Spectrum Antioxidants for Acute Kidney Injury Management Advanced Science (2020)

Selenium‐Doped Carbon Quantum Dots Act as Broad‐Spectrum Antioxidants for Acute Kidney Injury Management Advanced Science (2020)

Y-86/90-Labeled Monoclonal Antibody Targeting Tissue Factor for Pancreatic Cancer Theranostics Molecular Pharmaceutics (2020)

Dual-labeled pertuzumab for multimodality image-guided ovarian tumor resection. American journal of cancer research (2019)

Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models. American journal of cancer research (2019)

A "Missile-Detonation" Strategy to Precisely Supply and Efficiently Amplify Cerenkov Radiation Energy for Cancer Theranostics Advanced Materials (2019)

A “Missile-Detonation” Strategy to Precisely Supply and Efficiently Amplify Cerenkov Radiation Energy for Cancer Theranostics Advanced Materials (2019)

A “Missile‐Detonation” Strategy to Precisely Supply and Efficiently Amplify Cerenkov Radiation Energy for Cancer Theranostics Advanced Materials (2019)

Antibody and fragment-based PET imaging of CTLA-4+T-cells in humanized mouse models American Journal of Cancer Research (2019)

Cerenkov Radiation-Induced Photodynamic Therapy Amplified by Magnetic Nanotheranostics Journal of Nuclear Medicine (2019)

Ceria Nanoparticles Meet Hepatic Ischemia-Reperfusion Injury: The Perfect Imperfection Advanced Materials (2019)

Ceria Nanoparticles Meet Hepatic Ischemia‐Reperfusion Injury: The Perfect Imperfection Advanced Materials (2019)

Cu-68-labeled F(ab')(2) fragments of daratumumab for early visualization of CD38-positive lymphoma Journal of Nuclear Medicine (2019)

Imaging CTLA-4+T-cells in humanized mouse models Journal of Nuclear Medicine (2019)

Imaging PD-L1 expression in tumors follo ng radiotherapy treatment Journal of Nuclear Medicine (2019)

Manganese ions chelated melanin ultra-small nanostructure for PET/MR bimodal imaging-guided acute kidney injury therapy Journal of Nuclear Medicine (2019)

Noninvasive visualization of the differential expression of CD146 in breast cancer Journal of Nuclear Medicine (2019)

PET imaging of pre-synaptic protein SV2A in Rett syndrome mouse model Journal of Nuclear Medicine (2019)

Polyoxometalate Clusters as Multi-antioxidants to Ameliorate Acute Kidney Injury in Mice Journal of Nuclear Medicine (2019)

Radionuclide-Activated Nanomaterials and Their Biomedical Applications Angewandte Chemie International Edition (2019)

Radionuclide‐Activated Nanomaterials and Their Biomedical Applications Angewandte Chemie International Edition (2019)

Renal-Accumulating Selenium-Doped Carbon Quantum Dots Treat Acute Kidney Injury in Mice Journal of Nuclear Medicine (2019)

Safe and dosimetry evaluation of radimmmunotherapy using Lu-177-labeled antibodies in lymphoma Journal of Nuclear Medicine (2019)

Size-Optimized Ultrasmall Porous Silica Nanoparticles Depict Vasculature-Based Differential Targeting in Triple Negative Breast Cancer Small (2019)

Size‐Optimized Ultrasmall Porous Silica Nanoparticles Depict Vasculature‐Based Differential Targeting in Triple Negative Breast Cancer Small (2019)

Surfactant-Stripped Pheophytin Micelles for Multimodal Tumor Imaging and Photodynamic Therapy ACS Applied Bio Materials (2019)

Y-86/90-based theranostics targeting tissue factor in a pancreatic tumor model Journal of Nuclear Medicine (2019)

Zirconium-89 radiolabeled hollow ferulic acid nanostructure for PET imaging guided acute kidney injury therapy Journal of Nuclear Medicine (2019)

Efficient Uptake of ¹⁷⁷Lu‐Porphyrin‐PEG Nanocomplexes by Tumor Mitochondria for Multimodal‐Imaging‐Guided Combination Therapy Angewandte Chemie (2018)

Activatable Hybrid Nanotheranostics for Tetramodal Imaging and Synergistic Photothermal/Photodynamic Therapy Advanced Materials (2018)

Antiangiogenic evaluation of ZnWO4 nanoparticles synthesised through microwave-assisted hydrothermal method Journal of Drug Targeting (2018)

Antiangiogenic evaluation of ZnWO₄ nanoparticles synthesised through microwave-assisted hydrothermal method Journal of Drug Targeting (2018)

DNA tetrahedron nanoparticles enable kidney function assessment in mice with unilateral ureteral obstruction Journal of Nuclear Medicine (2018)

Effective weight control via an implanted self-powered vagus nerve stimulation device Nature Communications (2018)

Efficient Uptake of Lu-177-Porphyrin-PEG Nanocomplexes by Tumor Mitochondria for Multimodal-Imaging-Guided Combination Therapy Angewandte Chemie International Edition (2018)

Efficient Uptake of ¹⁷⁷Lu-Porphyrin-PEG Nanocomplexes by Tumor Mitochondria for Multimodal-Imaging-Guided Combination Therapy Angewandte Chemie - International Edition (2018)

Exogenous Radionanomedicine: Inorganic Nanomaterials Radionanomedicine: Combined Nuclear and Nanomedicine (2018)

ImmunoPET of CD146 in a Murine Hindlimb Ischemia Model Molecular Pharmaceutics (2018)

Implanted Battery-Free Direct-Current Micro-Power Supply from in Vivo Breath Energy Harvesting ACS Applied Materials & Interfaces (2018)

In vivo PET imaging of CD20 using Cu-64-labeled F(ab)2 fragment of obinumumab in lymphoma models Journal of Nuclear Medicine (2018)

Magnetic Targeting of Nanotheranostics Enhances Cerenkov Radiation-Induced Photodynamic Therapy Journal of the American Chemical Society (2018)

Markedly Enhanced Magnetic Resonance Imaging-Guided Photothermal Therapy with Oxygen Vacancy Regulation Journal of Nuclear Medicine (2018)

Radiolabeled Nanostructured Porphyrin-PEG Mesh for Efficient Tumor Targeting and Multimodal Image-Guided Combination Therapy Journal of Nuclear Medicine (2018)

Scavenging of reactive oxygen and nitrogen species with nanomaterials Nano Research (2018)

Targeting angiogenesis for radioimmunotherapy with a Lu-177-labeled antibody European Journal of Nuclear Medicine and Molecular Imaging (2018)

Targeting angiogenesis for radioimmunotherapy with a ¹⁷⁷Lu-labeled antibody European Journal of Nuclear Medicine and Molecular Imaging (2018)

Targeting angiogenesis for radioimmunotherapy with a 177Lu-labeled antibody European Journal of Nuclear Medicine and Molecular Imaging (2018)

Theranostics of Murine Breast Cancer with a 86/90Y-Labeled Antibody Medical Physics (2018)

Theranostics of lymphoma with Zr-89- and Lu-177-labeled daratumumab Journal of Nuclear Medicine (2018)

Vasculature-based differential tumor uptake of radiolabeled Ultrasmall Mesoporous Silica Nanoparticles in breast cancers models Journal of Nuclear Medicine (2018)

Vincristine-loaded hydroxyapatite nanoparticles as a potential delivery system for bone cancer therapy Journal of Drug Targeting (2018)

Y-86/90-Based Theranostics Targeting Angiogenesis in a Murine Breast Cancer Model Molecular Pharmaceutics (2018)

^86/90 Y-Based Theranostics Targeting Angiogenesis in a Murine Breast Cancer Model Molecular Pharmaceutics (2018)

^86/90Y-Based Theranostics Targeting Angiogenesis in a Murine Breast Cancer Model Molecular Pharmaceutics (2018)

Y-86/90-Labeled Ultrasmall Mesoporous Silica Nanoparticles for Cancer Theranostics Journal of Nuclear Medicine (2018)

Y-86/90-based theranostics of breast cancer in a preclinical model Journal of Nuclear Medicine (2018)

Radiolabeled bombesin derivatives for preclinical oncological imaging Biomedicine & Pharmacotherapy (2017)

The role of radionuclide probes for monitoring anti-tumor drugs efficacy: A brief review Biomedicine & Pharmacotherapy (2017)

Development of imaging probes for bone cancer in animal models. A systematic review Biomedicine & Pharmacotherapy (2016)

Engineering of radiolabeled iron oxide nanoparticles for dual-modality imaging Wiley Interdisciplinary Reviews-nanomedicine and Nanobiotechnology (2016)

Engineering of radiolabeled iron oxide nanoparticles for dual‐modality imaging WIREs Nanomedicine and Nanobiotechnology (2016)

Hydroxyapatite nanoparticles: preparation, characterization, and evaluation of their potential use in bone targeting: an animal study Nuclear Medicine Communications (2016)

Hydroxyapatite nanoparticles Nuclear Medicine Communications (2016)

Morphologic and Functional Study of Heterotopic Splenic Tissue Allografts in Rabbits. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation (2015)

Study of the Zircon Processing Aiming the Recovery of Zirconium and Silica Proceedings of the International Mining Congress and Exhibition of Turkey, IMCET (2015)

Aptamers directly radiolabeled with technetium-99m as a potential agent capable of identifying carcinoembryonic antigen (CEA) in tumor cells T84 Bioorganic & Medicinal Chemistry Letters (2014)

Aptamer Functionalized Nanoparticles for Cancer Targeting Journal of Molecular Pharmaceutics & Organic Process Research (2013)

Tc-99m-labeled bombesin analog for breast cancer identification Journal of Radioanalytical and Nuclear Chemistry (2013)

^99mTc-labeled bombesin analog for breast cancer identification Journal of Radioanalytical and Nuclear Chemistry (2013)

99mTc-labeled bombesin analog for breast cancer identification Journal of Radioanalytical and Nuclear Chemistry (2013)

Boron nitride nanotubes radiolabeled with ^99mTc: Preparation, physicochemical characterization, biodistribution study, and scintigraphic imaging in Swiss mice International Journal of Pharmaceutics (2012)

Boron nitride nanotubes radiolabeled with 99mTc: Preparation, physicochemical characterization, biodistribution study, and scintigraphic imaging in Swiss mice International Journal of Pharmaceutics (2012)

Kit formulation for ^99mTc-labeling of HYNIC-ΒAla-Bombesin _(7-14) Applied Radiation and Isotopes (2012)

Kit formulation for 99mTc-labeling of HYNIC-βAla-Bombesin(7–14) Applied Radiation and Isotopes (2012)

Bombesin derivative radiolabeled with technetium-99m as agent for tumor identification Bioorganic & Medicinal Chemistry Letters (2010)