Brian Johnson , PhD

Publications

Quantifying partial pathological response rate in prostate cancer patients who underwent neoadjuvant chemotherapy using a novel morphometric approach. Journal of pathology informatics (2025)

AOP 460: Antagonism of Smoothened receptor leading to orofacial clefting. ALTEX (2025)

Spatially dependent tissue distribution of thyroid hormones by plasma thyroid hormone binding proteins. Pflugers Archiv : European journal of physiology (2025)

The Asymmetry Within: A Renewed Look at Cupids Bow in Unilateral Cleft Lip. The Journal of craniofacial surgery (2024)

Crowdsourcing AOP development: Leveraging the thesis literature review to identify knowledge gaps and facilitate research translation Current Research in Toxicology (2024)

A minimal human physiologically based kinetic model of thyroid hormones and chemical disruption of plasma thyroid hormone binding proteins. Frontiers in endocrinology (2023)

Fresh tissue procurement and preparation for multicompartment and multimodal analysis of the prostate tumor microenvironment The Prostate (2022)

A Microphysiological Approach to Evaluate Effectors of Intercellular Hedgehog Signaling in Development. Frontiers in cell and developmental biology (2021)

A bioengineered organotypic prostate model for the study of tumor microenvironment-induced immune cell activation. Integrative biology : quantitative biosciences from nano to macro (2020)

Engineered Perineural Vascular Plexus for Modeling Developmental Toxicity. Advanced healthcare materials (2020)

Modeling chemical effects on breast cancer: the importance of the microenvironment in vitro. Integrative biology : quantitative biosciences from nano to macro (2020)

Mri-based cancer lesion analysis with 3d printed patient specific prostate cutting guides. American journal of clinical and experimental urology (2019)

Mammary adipose stromal cells derived from obese women reduce sensitivity to the aromatase inhibitor anastrazole in an organotypic breast model. FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2019)

Evaluation of PEG-based hydrogel influence on estrogen receptor driven responses in MCF7 breast cancer cells. ACS biomaterials science & engineering (2019)

Mammary fibroblasts reduce apoptosis and speed estrogen-induced hyperplasia in an organotypic MCF7-derived duct model. Scientific reports (2018)

Vital ex vivo tissue labeling and pathology-guided micropunching to characterize cellular heterogeneity in the tissue microenvironment. BioTechniques (2018)

Hepatic expression profiles in retroviral infection: relevance to drug hypersensitivity risk. Pharmacology research & perspectives (2017)

Personalized in vitro cancer models to predict therapeutic response: Challenges and a framework for improvement. Pharmacology & therapeutics (2016)

Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression. Clinical cancer research : an official journal of the American Association for Cancer Research (2016)

Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase. Proceedings of the National Academy of Sciences of the United States of America (2014)

Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice. Proceedings of the National Academy of Sciences of the United States of America (2014)

Aggregate culture of human embryonic stem cell-derived hepatocytes in suspension are an improved in vitro model for drug metabolism and toxicity testing. Toxicological sciences : an official journal of the Society of Toxicology (2014)

An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells. Journal of immunology (Baltimore, Md. : 1950) (2010)